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People who have succeeded using a combination of prescription medications and quality skin care products have stuck to a schedule and used their medications as directed by their doctors. In other words, they've established a care by skin type regimen. By doing so, they've not only enabled their prescription medications to do the job they were created to do, they've also reduced the likelihood of side effects or at least know how to combat them.
For example, it's best to wait 10 to 15 minutes after washing your face before applying topical acne medication. If you've waited but see redness, drying, or peeling, the irritation could be caused by your cleanser. Try to use alcohol free products. Always use a mild cleanser--one that feels non-abrasive and does not contain alcohol--on your face and other acne-prone areas. Using a noncomedogenic moisturizer (one that won't clog pores)immediately after applying the medication can reduce the redness, drying and peeling. Acne won't clear up overnight. After 6 to 8 weeks, you can expect to see about a 40% improvement. It takes 4 to 6 months to see significant improvement but worth the time and effort you put into it.